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The Identification of a Novel Gene, MAPO2, That Is Involved in the Induction of Apoptosis Triggered by O(6)-Methylguanine

O(6)-Methylguanine, one of alkylated DNA bases, is especially mutagenic. Cells containing this lesion are eliminated by induction of apoptosis, associated with the function of mismatch repair (MMR) proteins. A retrovirus-mediated gene-trap mutagenesis was used to isolate new genes related to the ind...

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Detalles Bibliográficos
Autores principales:	Fujikane, Ryosuke, Sanada, Masayuki, Sekiguchi, Mutsuo, Hidaka, Masumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454368/ https://www.ncbi.nlm.nih.gov/pubmed/23028632 http://dx.doi.org/10.1371/journal.pone.0044817

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