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Differential Regulation of Breast Cancer-Associated Genes by Progesterone Receptor Isoforms PRA and PRB in a New Bi-Inducible Breast Cancer Cell Line

Progesterone receptor isoforms (PRA and PRB) are expressed at equal levels in normal mammary cells. However, alteration in PRA/PRB expression is often observed in aggressive breast cancer suggesting differential contribution of PR isoforms in carcinogenesis. The mechanisms underlying such processes...

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Detalles Bibliográficos
Autores principales: Khan, Junaid A., Bellance, Catherine, Guiochon-Mantel, Anne, Lombès, Marc, Loosfelt, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454371/
https://www.ncbi.nlm.nih.gov/pubmed/23029355
http://dx.doi.org/10.1371/journal.pone.0045993