Targeting G with TAL Effectors: A Comparison of Activities of TALENs Constructed with NN and NK Repeat Variable Di-Residues

The DNA binding domain of Transcription Activator-Like (TAL) effectors can easily be engineered to have new DNA sequence specificities. Consequently, engineered TAL effector proteins have become important reagents for manipulating genomes in vivo. DNA binding by TAL effectors is mediated by arrays o...

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Detalles Bibliográficos
Autores principales: Christian, Michelle L., Demorest, Zachary L., Starker, Colby G., Osborn, Mark J., Nyquist, Michael D., Zhang, Yong, Carlson, Daniel F., Bradley, Philip, Bogdanove, Adam J., Voytas, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454392/
https://www.ncbi.nlm.nih.gov/pubmed/23028976
http://dx.doi.org/10.1371/journal.pone.0045383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454392/
https://www.ncbi.nlm.nih.gov/pubmed/23028976
http://dx.doi.org/10.1371/journal.pone.0045383

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