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The Transcriptional Profile of Mesenchymal Stem Cell Populations in Primary Osteoporosis Is Distinct and Shows Overexpression of Osteogenic Inhibitors

Primary osteoporosis is an age-related disease characterized by an imbalance in bone homeostasis. While the resorptive aspect of the disease has been studied intensely, less is known about the anabolic part of the syndrome or presumptive deficiencies in bone regeneration. Multipotent mesenchymal ste...

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Detalles Bibliográficos
Autores principales: Benisch, Peggy, Schilling, Tatjana, Klein-Hitpass, Ludger, Frey, Sönke P., Seefried, Lothar, Raaijmakers, Nadja, Krug, Melanie, Regensburger, Martina, Zeck, Sabine, Schinke, Thorsten, Amling, Michael, Ebert, Regina, Jakob, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454401/
https://www.ncbi.nlm.nih.gov/pubmed/23028809
http://dx.doi.org/10.1371/journal.pone.0045142