Pharmacogenetic Analysis of Pediatric Patients with Acute Lymphoblastic Leukemia: A Possible Association between Survival Rate and ITPA Polymorphism

Genetic polymorphisms are important factors in the effects and toxicity of chemotherapeutics. To analyze the pharmacogenetic and ethnic differences in chemotherapeutics, major genes implicated in the treatment of acute lymphoblastic leukemia (ALL) were analyzed. Eighteen loci of 16 genes in 100 pati...

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Detalles Bibliográficos
Autores principales: Kim, Hyery, Kang, Hyoung Jin, Kim, Hyo Jeong, Jang, Mi Kyung, Kim, Nam Hee, Oh, Yongtaek, Han, Byoung-Don, Choi, Ji-Yeob, Kim, Chul Woo, Lee, Ji Won, Park, Kyung Duk, Shin, Hee Young, Ahn, Hyo Seop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454425/
https://www.ncbi.nlm.nih.gov/pubmed/23029095
http://dx.doi.org/10.1371/journal.pone.0045558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454425/
https://www.ncbi.nlm.nih.gov/pubmed/23029095
http://dx.doi.org/10.1371/journal.pone.0045558

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