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MAGEB2 is Activated by Promoter Demethylation in Head and Neck Squamous Cell Carcinoma

PURPOSE: Although promoter hypermethylation has been an accepted means of tumor suppressor gene inactivation, activation of otherwise normally repressed proto-oncogenes by promoter demethylation has been infrequently documented. EXPERIMENTAL DESIGN: In this study we performed an integrative, whole-g...

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Detalles Bibliográficos
Autores principales: Pattani, Kavita M., Soudry, Ethan, Glazer, Chad A., Ochs, Michael F., Wang, Hao, Schussel, Juliana, Sun, Wenyue, Hennessey, Patrick, Mydlarz, Wojciech, Loyo, Myriam, Demokan, Semra, Smith, Ian M., Califano, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454438/
https://www.ncbi.nlm.nih.gov/pubmed/23029077
http://dx.doi.org/10.1371/journal.pone.0045534