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Denosumab: a new option in the treatment of bone metastases from urological cancers

Bone metastases often create serious clinical problems: they lead to poor performance status due to pathologic fractures, spinal cord compression and intractable pain, commonly referred to as skeletal-related events. The receptor activator of nuclear factor-κB (RANK), the RANK ligand (RANKL), and os...

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Detalles Bibliográficos
Autores principales: Yuasa, Takeshi, Yamamoto, Shinya, Urakami, Shinji, Fukui, Iwao, Yonese, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457675/
https://www.ncbi.nlm.nih.gov/pubmed/23055747
http://dx.doi.org/10.2147/OTT.S30578