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Mannan-modified Ad5-PTEN treatment combined with docetaxel improves the therapeutic effect in H22 tumor-bearing mice

BACKGROUND: It has been reported that the tumor suppressor gene, PTEN, which is inactivated in many malignant tumors, plays an important role in apoptosis, cell cycle arrest, cell migration, and cell spread. For cancer gene therapy, one of the most important problems is low gene transfection efficie...

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Detalles Bibliográficos
Autores principales: Liu, Zhongbing, Li, Jinwei, Li, Juan, Huang, Juan, Ke, Famin, Qi, Qiaona, Jiang, Xing, Zhong, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457678/
https://www.ncbi.nlm.nih.gov/pubmed/23055722
http://dx.doi.org/10.2147/IJN.S34022