Ginsenoside Rb1 Prevents MPP(+)-Induced Apoptosis in PC12 Cells by Stimulating Estrogen Receptors with Consequent Activation of ERK1/2, Akt and Inhibition of SAPK/JNK, p38 MAPK

Ginsenoside Rb1 shows neuroprotective effects in various neurons, including dopaminergic cells. However, the precise mechanisms of action are uncertain. In this paper, we examine whether Rb1 has a neuroprotective effect on MPP(+)-induced apoptosis and attempt to clarify the signaling pathway in PC12...

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Detalles Bibliográficos
Autores principales: Hashimoto, Ryo, Yu, Jing, Koizumi, Hideki, Ouchi, Yasuyoshi, Okabe, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457685/
https://www.ncbi.nlm.nih.gov/pubmed/23024694
http://dx.doi.org/10.1155/2012/693717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457685/
https://www.ncbi.nlm.nih.gov/pubmed/23024694
http://dx.doi.org/10.1155/2012/693717

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