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Simulated annealing reveals the kinetic activity of SGLT1, a member of the LeuT structural family
The Na(+)/glucose cotransporter (SGLT1) is the archetype of membrane proteins that use the electrochemical Na(+) gradient to drive uphill transport of a substrate. The crystal structure recently obtained for vSGLT strongly suggests that SGLT1 adopts the inverted repeat fold of the LeuT structural fa...
Autores principales: | Longpré, Jean-Philippe, Sasseville, Louis J., Lapointe, Jean-Yves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457693/ https://www.ncbi.nlm.nih.gov/pubmed/23008432 http://dx.doi.org/10.1085/jgp.201210822 |
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