Chemokine-dependent T cell migration requires aquaporin-3–mediated hydrogen peroxide uptake

Chemokine-dependent trafficking is indispensable for the effector function of antigen-experienced T cells during immune responses. In this study, we report that the water/glycerol channel aquaporin-3 (AQP3) is expressed on T cells and regulates their trafficking in cutaneous immune reactions. T cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Hara-Chikuma, Mariko, Chikuma, Shunsuke, Sugiyama, Yoshinori, Kabashima, Kenji, Verkman, Alan S., Inoue, Shintaro, Miyachi, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457725/
https://www.ncbi.nlm.nih.gov/pubmed/22927550
http://dx.doi.org/10.1084/jem.20112398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457725/
https://www.ncbi.nlm.nih.gov/pubmed/22927550
http://dx.doi.org/10.1084/jem.20112398

Ejemplares similares