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Chemokine-dependent T cell migration requires aquaporin-3–mediated hydrogen peroxide uptake
Chemokine-dependent trafficking is indispensable for the effector function of antigen-experienced T cells during immune responses. In this study, we report that the water/glycerol channel aquaporin-3 (AQP3) is expressed on T cells and regulates their trafficking in cutaneous immune reactions. T cell...
Autores principales: | Hara-Chikuma, Mariko, Chikuma, Shunsuke, Sugiyama, Yoshinori, Kabashima, Kenji, Verkman, Alan S., Inoue, Shintaro, Miyachi, Yoshiki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457725/ https://www.ncbi.nlm.nih.gov/pubmed/22927550 http://dx.doi.org/10.1084/jem.20112398 |
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