Dual-reactive B cells are autoreactive and highly enriched in the plasmablast and memory B cell subsets of autoimmune mice

Rare dual-reactive B cells expressing two types of Ig light or heavy chains have been shown to participate in immune responses and differentiate into IgG(+) cells in healthy mice. These cells are generated more often in autoreactive mice, leading us to hypothesize they might be relevant in autoimmun...

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Detalles Bibliográficos
Autores principales: Fournier, Emilie M., Velez, Maria-Gabriela, Leahy, Katelyn, Swanson, Cristina L., Rubtsov, Anatoly V., Torres, Raul M., Pelanda, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457739/
https://www.ncbi.nlm.nih.gov/pubmed/22927551
http://dx.doi.org/10.1084/jem.20120332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457739/
https://www.ncbi.nlm.nih.gov/pubmed/22927551
http://dx.doi.org/10.1084/jem.20120332

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