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Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is characterised by substantial loss of both upper and lower motor neuron function, with sensory and cognitive systems less affected. Though heritable forms of the disease have been described, the vast majority of cases are sporadic with poorly defined underlying...

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Detalles Bibliográficos
Autores principales: Peters, Owen M., Millership, Steven, Shelkovnikova, Tatyana A., Soto, Ileana, Keeling, Lora, Hann, Anthony, Marsh-Armstrong, Nicholas, Buchman, Vladimir L., Ninkina, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457776/
https://www.ncbi.nlm.nih.gov/pubmed/22750530
http://dx.doi.org/10.1016/j.nbd.2012.06.016