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Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is characterised by substantial loss of both upper and lower motor neuron function, with sensory and cognitive systems less affected. Though heritable forms of the disease have been described, the vast majority of cases are sporadic with poorly defined underlying...
Autores principales: | Peters, Owen M., Millership, Steven, Shelkovnikova, Tatyana A., Soto, Ileana, Keeling, Lora, Hann, Anthony, Marsh-Armstrong, Nicholas, Buchman, Vladimir L., Ninkina, Natalia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457776/ https://www.ncbi.nlm.nih.gov/pubmed/22750530 http://dx.doi.org/10.1016/j.nbd.2012.06.016 |
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