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Independent Regulation of Basal Neurotransmitter Release Efficacy by Variable Ca(2+) Influx and Bouton Size at Small Central Synapses

The efficacy of action potential evoked neurotransmitter release varies widely even among synapses supplied by the same axon, and the number of release-ready vesicles at each synapse is a major determinant of this heterogeneity. Here we identify a second, equally important, mechanism for release het...

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Detalles Bibliográficos
Autores principales: Ermolyuk, Yaroslav S., Alder, Felicity G., Henneberger, Christian, Rusakov, Dmitri A., Kullmann, Dimitri M., Volynski, Kirill E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457933/
https://www.ncbi.nlm.nih.gov/pubmed/23049481
http://dx.doi.org/10.1371/journal.pbio.1001396