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Peripheral Nervous System Neuropathology and Progressive Sensory Impairments in a Mouse Model of Mucopolysaccharidosis IIIB

The lysosomal storage pathology in Mucopolysaccharidosis (MPS) IIIB manifests in cells of virtually all organs. However, it is the profound role of the neurological pathology that leads to morbidity and mortality in this disease, and has been the major challenge to developing therapies. To date, MPS...

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Detalles Bibliográficos
Autores principales: Fu, Haiyan, Bartz, Julianne D., Stephens, Robert L., McCarty, Douglas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457935/
https://www.ncbi.nlm.nih.gov/pubmed/23049915
http://dx.doi.org/10.1371/journal.pone.0045992