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Chronic Zinc Exposure Decreases the Surface Expression of NR2A-Containing NMDA Receptors in Cultured Hippocampal Neurons

BACKGROUND: Zinc distributes widely in the central nervous system, especially in the hippocampus, amygdala and cortex. The dynamic balance of zinc is critical for neuronal functions. Zinc modulates the activity of N-methyl-D-aspartate receptors (NMDARs) through the direct inhibition and various intr...

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Detalles Bibliográficos
Autores principales: Zhu, Jia, Shao, Chong-Yu, Yang, Wei, Zhang, Xiao-Min, Wu, Zhen-Yong, Zhou, Liang, Wang, Xin-Xin, Li, Yun-Hong, Xia, Jun, Luo, Jian-Hong, Shen, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457937/
https://www.ncbi.nlm.nih.gov/pubmed/23049922
http://dx.doi.org/10.1371/journal.pone.0046012