Oral Vaccination with Lipid-Formulated BCG Induces a Long-lived, Multifunctional CD4(+) T Cell Memory Immune Response

Oral delivery of BCG in a lipid formulation (Liporale™-BCG) targets delivery of viable bacilli to the mesenteric lymph nodes and confers protection against an aerosol Mycobacterium tuberculosis challenge. The magnitude, quality and duration of the effector and memory immune response induced by Lipor...

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Detalles Bibliográficos
Autores principales: Ancelet, Lindsay R., Aldwell, Frank E., Rich, Fenella J., Kirman, Joanna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457949/
https://www.ncbi.nlm.nih.gov/pubmed/23049885
http://dx.doi.org/10.1371/journal.pone.0045888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457949/
https://www.ncbi.nlm.nih.gov/pubmed/23049885
http://dx.doi.org/10.1371/journal.pone.0045888

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