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Oral Vaccination with Lipid-Formulated BCG Induces a Long-lived, Multifunctional CD4(+) T Cell Memory Immune Response
Oral delivery of BCG in a lipid formulation (Liporale™-BCG) targets delivery of viable bacilli to the mesenteric lymph nodes and confers protection against an aerosol Mycobacterium tuberculosis challenge. The magnitude, quality and duration of the effector and memory immune response induced by Lipor...
Autores principales: | Ancelet, Lindsay R., Aldwell, Frank E., Rich, Fenella J., Kirman, Joanna R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457949/ https://www.ncbi.nlm.nih.gov/pubmed/23049885 http://dx.doi.org/10.1371/journal.pone.0045888 |
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