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Activation of Protease-Activated Receptor 2 Induces VEGF Independently of HIF-1

BACKGROUND: Human adipose stem cells (hASCs) can promote angiogenesis through secretion of proangiogenic factors such as vascular endothelial growth factor (VEGF). In other cell types, it has been shown that induction of VEGF is mediated by both protease activated receptor 2 (PAR2) and hypoxia induc...

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Detalles Bibliográficos
Autores principales: Rasmussen, Jeppe Grøndahl, Riis, Simone Elkjær, Frøbert, Ole, Yang, Sufang, Kastrup, Jens, Zachar, Vladimir, Simonsen, Ulf, Fink, Trine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457954/
https://www.ncbi.nlm.nih.gov/pubmed/23049945
http://dx.doi.org/10.1371/journal.pone.0046087