New Prediction Model for Probe Specificity in an Allele-Specific Extension Reaction for Haplotype-Specific Extraction (HSE) of Y Chromosome Mixtures

Allele-specific extension reactions (ASERs) use 3′ terminus-specific primers for the selective extension of completely annealed matches by polymerase. The ability of the polymerase to extend non-specific 3′ terminal mismatches leads to a failure of the reaction, a process that is only partly underst...

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Detalles Bibliográficos
Autores principales: Rothe, Jessica, Watkins, Norman E., Nagy, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457965/
https://www.ncbi.nlm.nih.gov/pubmed/23049901
http://dx.doi.org/10.1371/journal.pone.0045955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457965/
https://www.ncbi.nlm.nih.gov/pubmed/23049901
http://dx.doi.org/10.1371/journal.pone.0045955

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