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Met Kinetic Signature Derived from the Response to HGF/SF in a Cellular Model Predicts Breast Cancer Patient Survival

To determine the signaling pathways leading from Met activation to metastasis and poor prognosis, we measured the kinetic gene alterations in breast cancer cell lines in response to HGF/SF. Using a network inference tool we analyzed the putative protein-protein interaction pathways leading from Met...

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Detalles Bibliográficos
Autores principales: Stein, Gideon Y., Yosef, Nir, Reichman, Hadar, Horev, Judith, Laser-Azogui, Adi, Berens, Angelique, Resau, James, Ruppin, Eytan, Sharan, Roded, Tsarfaty, Ilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457970/
https://www.ncbi.nlm.nih.gov/pubmed/23049908
http://dx.doi.org/10.1371/journal.pone.0045969