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Hypoxia Induces PDK4 Gene Expression through Induction of the Orphan Nuclear Receptor ERRγ
Multiple cellular signaling pathways that control metabolism and survival are activated when cell are incubated under hypoxic conditions. Activation of the hypoxia inducible factor (HIF)-1 promotes expression of genes that increase the capacity to cope with the stress imposed by a reduced oxygen env...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457976/ https://www.ncbi.nlm.nih.gov/pubmed/23050013 http://dx.doi.org/10.1371/journal.pone.0046324 |