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Epstein-Barr virus Peptide Presented by HLA-E is Predominantly Recognized by CD8(bright) Cells in multiple Sclerosis Patients

Multiple sclerosis (MS) is associated with Epstein-Barr virus (EBV) infection, but impaired immune suppression may be part of the disease pathogenesis. CD8(+) T cells that are restricted by HLA-E exert an important immunoregulatory mechanism. To explore how EBV might interfere with immune regulation...

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Detalles Bibliográficos
Autores principales: Jørgensen, Pernille B., Livbjerg, Astrid H., Hansen, Hans J., Petersen, Thor, Höllsberg, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457977/
https://www.ncbi.nlm.nih.gov/pubmed/23049954
http://dx.doi.org/10.1371/journal.pone.0046120