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Gene Expression Responses to FUS, EWS, and TAF15 Reduction and Stress Granule Sequestration Analyses Identifies FET-Protein Non-Redundant Functions

The FET family of proteins is composed of FUS/TLS, EWS/EWSR1, and TAF15 and possesses RNA- and DNA-binding capacities. The FET-proteins are involved in transcriptional regulation and RNA processing, and FET-gene deregulation is associated with development of cancer and protein granule formations in...

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Detalles Bibliográficos
Autores principales: Blechingberg, Jenny, Luo, Yonglun, Bolund, Lars, Damgaard, Christian Kroun, Nielsen, Anders Lade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457980/
https://www.ncbi.nlm.nih.gov/pubmed/23049996
http://dx.doi.org/10.1371/journal.pone.0046251