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Gene Expression Responses to FUS, EWS, and TAF15 Reduction and Stress Granule Sequestration Analyses Identifies FET-Protein Non-Redundant Functions
The FET family of proteins is composed of FUS/TLS, EWS/EWSR1, and TAF15 and possesses RNA- and DNA-binding capacities. The FET-proteins are involved in transcriptional regulation and RNA processing, and FET-gene deregulation is associated with development of cancer and protein granule formations in...
Autores principales: | Blechingberg, Jenny, Luo, Yonglun, Bolund, Lars, Damgaard, Christian Kroun, Nielsen, Anders Lade |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457980/ https://www.ncbi.nlm.nih.gov/pubmed/23049996 http://dx.doi.org/10.1371/journal.pone.0046251 |
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