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Precise Mapping of the CD95 Pre-Ligand Assembly Domain

Pre-association of CD95 at the plasma membrane is mandatory for efficient death receptor signaling. This homotrimerization occurs through self-association of an extracellular domain called the pre-ligand assembly domain (PLAD). Using novel molecular and cellular tools, we confirmed that CD95-PLAD is...

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Detalles Bibliográficos
Autores principales: Edmond, Valérie, Ghali, Benoist, Penna, Aubin, Taupin, Jean-Luc, Daburon, Sophie, Moreau, Jean-François, Legembre, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457997/
https://www.ncbi.nlm.nih.gov/pubmed/23049989
http://dx.doi.org/10.1371/journal.pone.0046236