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Polymorphisms in the Human Tropoelastin Gene Modify In Vitro Self-Assembly and Mechanical Properties of Elastin-Like Polypeptides

Elastin is a major structural component of elastic fibres that provide properties of stretch and recoil to tissues such as arteries, lung and skin. Remarkably, after initial deposition of elastin there is normally no subsequent turnover of this protein over the course of a lifetime. Consequently, el...

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Detalles Bibliográficos
Autores principales: He, David, Miao, Ming, Sitarz, Eva E., Muiznieks, Lisa D., Reichheld, Sean, Stahl, Richard J., Keeley, Fred W., Parkinson, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458006/
https://www.ncbi.nlm.nih.gov/pubmed/23049958
http://dx.doi.org/10.1371/journal.pone.0046130