A Single-Day Treatment with Mifepristone Is Sufficient to Normalize Chronic Glucocorticoid Induced Suppression of Hippocampal Cell Proliferation

BACKGROUND: Chronic stress or prolonged administration of glucocorticoids suppresses proliferation and/or survival of newborn cells in adult rat dentate gyrus. Earlier we showed that administration of the glucocorticoid receptor antagonist mifepristone during the final 4 days of a 21 days period of...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Pu, Oomen, Charlotte, van Dam, Anne-Marie, Wester, Jordi, Zhou, Jiang-Ning, Joëls, Marian, Lucassen, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458013/
https://www.ncbi.nlm.nih.gov/pubmed/23049985
http://dx.doi.org/10.1371/journal.pone.0046224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458013/
https://www.ncbi.nlm.nih.gov/pubmed/23049985
http://dx.doi.org/10.1371/journal.pone.0046224

Ejemplares similares