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A Single-Day Treatment with Mifepristone Is Sufficient to Normalize Chronic Glucocorticoid Induced Suppression of Hippocampal Cell Proliferation
BACKGROUND: Chronic stress or prolonged administration of glucocorticoids suppresses proliferation and/or survival of newborn cells in adult rat dentate gyrus. Earlier we showed that administration of the glucocorticoid receptor antagonist mifepristone during the final 4 days of a 21 days period of...
Autores principales: | Hu, Pu, Oomen, Charlotte, van Dam, Anne-Marie, Wester, Jordi, Zhou, Jiang-Ning, Joëls, Marian, Lucassen, Paul J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458013/ https://www.ncbi.nlm.nih.gov/pubmed/23049985 http://dx.doi.org/10.1371/journal.pone.0046224 |
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