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High-Throughput Screening for Novel Inhibitors of Neisseria gonorrhoeae Penicillin-Binding Protein 2

The increasing prevalence of N. gonorrhoeae strains exhibiting decreased susceptibility to third-generation cephalosporins and the recent isolation of two distinct strains with high-level resistance to cefixime or ceftriaxone heralds the possible demise of β-lactam antibiotics as effective treatment...

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Detalles Bibliográficos
Autores principales: Fedarovich, Alena, Djordjevic, Kevin A., Swanson, Shauna M., Peterson, Yuri K., Nicholas, Robert A., Davies, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458020/
https://www.ncbi.nlm.nih.gov/pubmed/23049763
http://dx.doi.org/10.1371/journal.pone.0044918