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A CD44(high)/EGFR(low) Subpopulation within Head and Neck Cancer Cell Lines Shows an Epithelial-Mesenchymal Transition Phenotype and Resistance to Treatment

Mortality in head and neck squamous cell carcinoma (HNSCC) is high due to emergence of therapy resistance which results in local and regional recurrences that may have their origin in resistant cancer stem cells (CSCs) or cells with an epithelial-mesenchymal transition (EMT) phenotype. In the presen...

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Detalles Bibliográficos
Autores principales: La Fleur, Linnea, Johansson, Ann-Charlotte, Roberg, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458050/
https://www.ncbi.nlm.nih.gov/pubmed/23049743
http://dx.doi.org/10.1371/journal.pone.0044071