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Standardization of the Teratoma Assay for Analysis of Pluripotency of Human ES Cells and Biosafety of Their Differentiated Progeny

Teratoma tumor formation is an essential criterion in determining the pluripotency of human pluripotent stem cells. However, currently there is no consistent protocol for assessment of teratoma forming ability. Here we present detailed characterization of a teratoma assay that is based on subcutaneo...

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Detalles Bibliográficos
Autores principales: Gropp, Michal, Shilo, Vitali, Vainer, Gilad, Gov, Miri, Gil, Yaniv, Khaner, Hanita, Matzrafi, Limor, Idelson, Maria, Kopolovic, Juri, Zak, Naomi B., Reubinoff, Benjamin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458078/
https://www.ncbi.nlm.nih.gov/pubmed/23049812
http://dx.doi.org/10.1371/journal.pone.0045532