Paralogous ALT1 and ALT2 Retention and Diversification Have Generated Catalytically Active and Inactive Aminotransferases in Saccharomyces cerevisiae

BACKGROUND: Gene duplication and the subsequent divergence of paralogous pairs play a central role in the evolution of novel gene functions. S. cerevisiae possesses two paralogous genes (ALT1/ALT2) which presumably encode alanine aminotransferases. It has been previously shown that Alt1 encodes an a...

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Detalles Bibliográficos
Autores principales: Peñalosa-Ruiz, Georgina, Aranda, Cristina, Ongay-Larios, Laura, Colon, Maritrini, Quezada, Hector, Gonzalez, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458083/
https://www.ncbi.nlm.nih.gov/pubmed/23049841
http://dx.doi.org/10.1371/journal.pone.0045702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458083/
https://www.ncbi.nlm.nih.gov/pubmed/23049841
http://dx.doi.org/10.1371/journal.pone.0045702

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