A Systematic Investigation of Differential Effects of Cell Culture Substrates on the Extent of Artifacts in Single-Molecule Tracking

Single-molecule techniques are being increasingly applied to biomedical investigation, notwithstanding the numerous challenges they pose in terms of signal-to-noise ratio issues. Non-specific binding of probes to glass substrates, in particular, can produce experimental artifacts due to spurious mol...

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Detalles Bibliográficos
Autores principales: Zanetti-Domingues, Laura C., Martin-Fernandez, Marisa L., Needham, Sarah R., Rolfe, Daniel J., Clarke, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458086/
https://www.ncbi.nlm.nih.gov/pubmed/23049831
http://dx.doi.org/10.1371/journal.pone.0045655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458086/
https://www.ncbi.nlm.nih.gov/pubmed/23049831
http://dx.doi.org/10.1371/journal.pone.0045655

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