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A Systematic Investigation of Differential Effects of Cell Culture Substrates on the Extent of Artifacts in Single-Molecule Tracking
Single-molecule techniques are being increasingly applied to biomedical investigation, notwithstanding the numerous challenges they pose in terms of signal-to-noise ratio issues. Non-specific binding of probes to glass substrates, in particular, can produce experimental artifacts due to spurious mol...
Autores principales: | Zanetti-Domingues, Laura C., Martin-Fernandez, Marisa L., Needham, Sarah R., Rolfe, Daniel J., Clarke, David T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458086/ https://www.ncbi.nlm.nih.gov/pubmed/23049831 http://dx.doi.org/10.1371/journal.pone.0045655 |
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