Orchestrated experience-driven Arc/Arg3.1 responses are disrupted in a mouse model of Alzheimer’s disease

Experience-induced expression of immediate-early gene Arc/Arg3.1 is known to play a pivotal role in the consolidation of memory. Here we use in-vivo longitudinal multiphoton imaging to show orchestrated activity-dependent expression of Arc in the mouse extrastriate visual cortex in response to a str...

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Detalles Bibliográficos
Autores principales: Rudinskiy, Nikita, Hawkes, Jonathan M., Betensky, Rebecca A., Eguchi, Megumi, Yamaguchi, Shun, Spires-Jones, Tara L., Hyman, Bradley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458168/
https://www.ncbi.nlm.nih.gov/pubmed/22922786
http://dx.doi.org/10.1038/nn.3199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458168/
https://www.ncbi.nlm.nih.gov/pubmed/22922786
http://dx.doi.org/10.1038/nn.3199

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