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Orchestrated experience-driven Arc/Arg3.1 responses are disrupted in a mouse model of Alzheimer’s disease
Experience-induced expression of immediate-early gene Arc/Arg3.1 is known to play a pivotal role in the consolidation of memory. Here we use in-vivo longitudinal multiphoton imaging to show orchestrated activity-dependent expression of Arc in the mouse extrastriate visual cortex in response to a str...
Autores principales: | Rudinskiy, Nikita, Hawkes, Jonathan M., Betensky, Rebecca A., Eguchi, Megumi, Yamaguchi, Shun, Spires-Jones, Tara L., Hyman, Bradley T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458168/ https://www.ncbi.nlm.nih.gov/pubmed/22922786 http://dx.doi.org/10.1038/nn.3199 |
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