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Self-repair in a bidirectionally coupled astrocyte-neuron (AN) system based on retrograde signaling

In this paper we demonstrate that retrograde signaling via astrocytes may underpin self-repair in the brain. Faults manifest themselves in silent or near silent neurons caused by low transmission probability (PR) synapses; the enhancement of the transmission PR of a healthy neighboring synapse by re...

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Detalles Bibliográficos
Autores principales: Wade, John, McDaid, Liam, Harkin, Jim, Crunelli, Vincenzo, Kelso, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458420/
https://www.ncbi.nlm.nih.gov/pubmed/23055965
http://dx.doi.org/10.3389/fncom.2012.00076