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Inferring direct DNA binding from ChIP-seq

Genome-wide binding data from transcription factor ChIP-seq experiments is the best source of information for inferring the relative DNA-binding affinity of these proteins in vivo. However, standard motif enrichment analysis and motif discovery approaches sometimes fail to correctly identify the bin...

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Detalles Bibliográficos
Autores principales: Bailey, Timothy L., Machanick, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458523/
https://www.ncbi.nlm.nih.gov/pubmed/22610855
http://dx.doi.org/10.1093/nar/gks433