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A new method for evaluating the specificity of indirect readout in protein–DNA recognition

Proteins recognize a specific DNA sequence not only through direct contact (direct readout) with base pairs but also through sequence-dependent conformation and/or flexibility of DNA (indirect readout). However, it is difficult to assess the contribution of indirect readout to the sequence specifici...

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Detalles Bibliográficos
Autores principales: Yamasaki, Satoshi, Terada, Tohru, Kono, Hidetoshi, Shimizu, Kentaro, Sarai, Akinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458528/
https://www.ncbi.nlm.nih.gov/pubmed/22618872
http://dx.doi.org/10.1093/nar/gks462