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Molecular engineering of G-quadruplex ligands based on solvent effect of polyethylene glycol

Because various non-parallel G-quadruplexes of human telomeric sequences in K(+) solution can be converted to a parallel G-quadruplex by adding polyethylene glycol (PEG) as a co-solvent, we have taken advantage of this property of PEG to study the covalent attachment of a PEG unit to a G-quadruplex...

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Detalles Bibliográficos
Autores principales: Wang, Zi-Fu, Chang, Ta-Chau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458535/
https://www.ncbi.nlm.nih.gov/pubmed/22735707
http://dx.doi.org/10.1093/nar/gks578