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Discovery, optimization and validation of an optimal DNA-binding sequence for the Six1 homeodomain transcription factor

The Six1 transcription factor is a homeodomain protein involved in controlling gene expression during embryonic development. Six1 establishes gene expression profiles that enable skeletal myogenesis and nephrogenesis, among others. While several homeodomain factors have been extensively characterize...

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Detalles Bibliográficos
Autores principales: Liu, Yubing, Nandi, Soumyadeep, Martel, André, Antoun, Alen, Ioshikhes, Ilya, Blais, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458543/
https://www.ncbi.nlm.nih.gov/pubmed/22730291
http://dx.doi.org/10.1093/nar/gks587