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NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3

Cytoplasmic polyadenylation element-binding protein (CPEB)3 is a nucleocytoplasm-shuttling RNA-binding protein and predominantly resides in the cytoplasm where it represses target RNA translation. When translocated into the nucleus, CPEB3 binds to Stat5b and downregulates Stat5b-dependent transcript...

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Detalles Bibliográficos
Autores principales: Chao, Hsu-Wen, Lai, Yen-Ting, Lu, Yi-Ling, Lin, Chi-long, Mai, Wei, Huang, Yi-Shuian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458550/
https://www.ncbi.nlm.nih.gov/pubmed/22730302
http://dx.doi.org/10.1093/nar/gks598