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MyoD regulates p57(kip2) expression by interacting with a distant cis-element and modifying a higher order chromatin structure
The bHLH transcription factor MyoD, the prototypical master regulator of differentiation, directs a complex program of gene expression during skeletal myogenesis. The up-regulation of the cdk inhibitor p57(kip2) plays a critical role in coordinating differentiation and growth arrest during muscle de...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458561/ https://www.ncbi.nlm.nih.gov/pubmed/22740650 http://dx.doi.org/10.1093/nar/gks619 |