RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo

In this study, we demonstrate that the lack of retinoic acid-related orphan receptor (ROR) γ or α expression in mice significantly reduced the peak expression level of Cry1, Bmal1, E4bp4, Rev-Erbα and Per2 in an ROR isotype- and tissue-selective manner without affecting the phase of their rhythmic e...

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Detalles Bibliográficos
Autores principales: Takeda, Yukimasa, Jothi, Raja, Birault, Veronique, Jetten, Anton M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458568/
https://www.ncbi.nlm.nih.gov/pubmed/22753030
http://dx.doi.org/10.1093/nar/gks630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458568/
https://www.ncbi.nlm.nih.gov/pubmed/22753030
http://dx.doi.org/10.1093/nar/gks630

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