Crystal structure of the UvrB dimer: insights into the nature and functioning of the UvrAB damage engagement and UvrB–DNA complexes

UvrB has a central role in the highly conserved UvrABC pathway functioning not only as a damage recognition element but also as an essential component of the lesion tracking machinery. While it has been recently confirmed that the tracking assembly comprises a UvrA(2)B(2) heterotetramer, the configu...

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Detalles Bibliográficos
Autores principales: Webster, Matthew P. J., Jukes, Rachael, Zamfir, Vlad S., Kay, Christopher W. M., Bagnéris, Claire, Barrett, Tracey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458569/
https://www.ncbi.nlm.nih.gov/pubmed/22753105
http://dx.doi.org/10.1093/nar/gks633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458569/
https://www.ncbi.nlm.nih.gov/pubmed/22753105
http://dx.doi.org/10.1093/nar/gks633

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