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HnRNP A1 phosphorylated by VRK1 stimulates telomerase and its binding to telomeric DNA sequence
The telomere integrity is maintained via replication machinery, telomere associated proteins and telomerase. Many telomere associated proteins are regulated in a cell cycle-dependent manner. Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1), a single-stranded oligonucleotide binding protein, is...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458570/ https://www.ncbi.nlm.nih.gov/pubmed/22740652 http://dx.doi.org/10.1093/nar/gks634 |