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HnRNP A1 phosphorylated by VRK1 stimulates telomerase and its binding to telomeric DNA sequence

The telomere integrity is maintained via replication machinery, telomere associated proteins and telomerase. Many telomere associated proteins are regulated in a cell cycle-dependent manner. Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1), a single-stranded oligonucleotide binding protein, is...

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Detalles Bibliográficos
Autores principales: Choi, Yoon Ha, Lim, Jong-Kwan, Jeong, Min-Woo, Kim, Kyong-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458570/
https://www.ncbi.nlm.nih.gov/pubmed/22740652
http://dx.doi.org/10.1093/nar/gks634